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Publication Type: OBS Messages
Single or Multiple Incident: Multiple
Date: 11/9/2018 12:00:00 AM
Country: Denmark
This alert discusses the dosing errors that can occur with the Xarelto® (rivaroxaban) Starter Kit. The starter pack contains tablets with two different strengths; included are 42 tablets of 15 mg and 7 tablets of 20 mg. Two different dosages are required during a prescribing period. The recommended dosage is: initially 15 mg twice daily for three weeks, then 20 mg once daily. As this is a high-alert anticoagulant, blood disorders can occur with the wrong dosage. The alert provides direction on how to avoid dosing errors with this medication package.

Additional Details

Medication/Gas/Fluid:
antithrombotic agent, rivaroxaban (Xarelto®)
Medication/IV List:
antithrombotic agents (anticoagulants)

Rules / Policies / Procedures
  1. Pay special attention to dosing when prescribing Xarelto® Starter Kit. It is important that the dosing instructions are unambiguous with regard to the strength of the tablets.
Training
  1. Make sure that the patient understands how to take the tablets and that there is a change in dosage over the period.

Be aware of the risk of incorrect dosing with Xarelto® Starter Kit