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Publication Type: Notes message
Single or Multiple Incident: Multiple
Date: 6/13/2017 12:00:00 AM
Country: Denmark

This alert discusses the patient safety incidents that can occur with the sedating antihistamine, cyclizine. Cyclizine is available without prescription as an over-the-counter (otc) medication and has been used for suicide attempts. Four cases are referenced, one of which was fatal. The alert advises on the correct dose of cyclizine in children, adults and the elderly, common side effects, overdose symptoms and the additive sedative effect when combined with other anti-anxiety agents, sedatives, or anti-psychotics.

Additional Details

Medication/Gas/Fluid:
sedatives, anti-anxiety agents, anti-psychotics, antihistamines, cyclizine (Gotur®, Marzine®), alcohol


Deliberate overdose with cyclizine (Gotur and Marzine®)