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Publication Type: Safety Notice
Single or Multiple Incident: Multiple
Date: 5/14/2021 12:00:00 AM
Country: Australia

This Safety Notice discusses recent poisoning from opioid toxicity following nasal insufflation of illicit cocaine. The clinical findings suggest a potent and long-acting opioid is involved with preliminary toxicology testing confirming the presence of opioids with further testing underway. Prior Safety Notices 009/20 and 011/20 have reported fentanyl/acetylfentanyl toxicity in non-opioid illicit substances such as cocaine. Continuing changes in illicit drug use and supply in 2021 may be associated with overdose risk. Variations in purity and substitution for alternative ingredients in currently circulating illicit drugs may be contributing to the problem. The notice provides case management recommendations to address this issue.

Additional Details

Medication/Gas/Fluid:
opioids, synthetic opioids, cocaine, heroin, fentanyl, acetylfentanyl, naloxone, oxygen
Medication/IV List:
narcotics/opiates, IV, transdermal, and oral (including liquid concentrates, immediate and sustained-release formulations)


Illicit cocaine containing strong opioids