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Publication Type: Patient Safety Alert
Single or Multiple Incident: Multiple
Date: 5/7/2019 12:00:00 AM
Country: South Korea

This alert discusses hypersensitivity reactions after patients were administered contrast agents. Two cases are described where a severe reaction resulted in hypoxic brain damage in one case; in the other case a hypersensitivity reaction requiring cardiopulmonary resuscitation occurred despite a negative skin reaction test. Recommendations addressing pre-inspection cautions, post-examination observation and process for responding to hypersensitivity reactions are provided. In addition a treatment algorithm for outpatient and radiology treatment of mild and severe hypersensitivity cases is provided.

Additional Details

intravenous injection equipment, airway maintenance equipment
radiocontrast agents, antihistamine, chlorpheniramine, epinephrine, epinephrine self-injection kit, steroids, prednisone, methylprednisolone, hydrocortisone injectable, fast actine bronchial dilators, normal saline, oxygen
Medication/IV List:
adrenergic agonists, IV (e.g., epinephrine, phenylephrine, norepinephrine, dopamine), radiocontrast agents, IV

Hypersensitivity reaction after administration of contrast agent