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​Professional Associations and He​lpful Websites

VTE Clinical Practice Guidelines

*(key resources recommended by Dr. W. Geerts)​

*Safer Healthcare Now! Venous Thromboembolism (VTE): Getting Started Kit. Safer Healthcare Now!, 2012.

Bates SM, Greer IA, Middeldorp S, Veenstra DL, Prabulos AM, Vandvik PO. VTE, thrombophilia, antithrombotic therapy, and pregnancy: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012; 141 (2 Suppl): e691S-e736S.

Chan WS, Rey E, Kent NE, VTE in Pregnancy Guideline Working Group, et al. Society of Obstetricians and Gynaecologists of Canada (SOGC) Clinical Practice Guidelines: Venous thromboembolism and antithrombotic therapy in pregnancy. J Obstet Gynaecol Can. 2014; 36 (6): 527–553.

Falck-Ytter Y, Francis CW, Johanson NA, Curley C, Dahl OE, Schulman S, et al. Prevention of VTE in orthopedic surgery patients: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012; 141 (2 Suppl): e278S-e325S. doi: 10.1378/chest.11-2404.

Farge D, Debourdeau P, Beckers M, Baglin C, Bauersachs RM, Brenner B, et al. International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer. JThrombHaemost. 2013; 11 (1): 56-70. doi: 10.1111/jth.12070.

Gould MK, Garcia DA, Wren SM, Karanicolas PJ, Arcelus JI, Heit JA, et al. Prevention of VTE in nonorthopedic surgical patients: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012; 141 (2 Suppl): e227S-e277S. doi: 10.1378/chest.11-2297.

Kahn SR, Lim W, Dunn AS, Cushman M, Dentail F, Akl EA, et al. Prevention of VTE in nonsurgical patients: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012; 141 (2 Suppl): e195S-e226S. doi: 10.1378/chest.11-2296.

Lyman GH, Bohlke K, Khorana AA, Kuderer NJM, Lee AY, Arcelus JI, et al. Venous thromboembolism prophylaxis and treatment in patients with cancer: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2015; 33 (6): 654-656. doi: 10.1200/JCO.2014.59.7351.

VTE Prevention Reso​urces

*(key resources recommended by Dr. W. Geerts)​​

Beeler PE, Kucher N, Blaser J. Sustained impact of electronic alerts on rate of prophylaxis against venous thromboembolism. Thromb Haemost. 2011; 106 (4): 734-738. doi: 10.1160/TH11-04-0220.

Bernier MC, Desjardins K, Filiatrault J, Sauriol MA, Martineau J, Gilbert E, et al. Implementation and evaluation of a pharmacy-led thromboprophylaxis campaign in a community hospital. J Thromb Thrombolysis. 2011; 32 (4): 431-438. doi: 10.1007/s11239-011-0614-5.

Duff J, Omari A, Middleton S, McInnes E, Walker K. Educational outreach visits to improve venous thromboembolism prevention in hospitalised medical patients: a prospective before-and-after intervention study. BMC Health Serv Res. 2013; 13: 398.    

Duff J, Walker K, Omari A, Middleton S, McInnes E. Educational outreach visits to improve nurses' use of mechanical venous thromboembolism prevention in hospitalized medical patients. J Vasc Nurs. 2013; 31 (4): 139-149. doi: 10.1016/j.jvn.2013.04.002.

Duff J, Walker K, Omari A, Stratton C. Prevention of venous thromboembolism in hospitalized patients: analysis of reduced cost and improved clinical outcomes. J Vasc Nurs. 2013; 31 (1): 9-14. doi: 10.1016/j.jvn.2012.06.006.

Gibbs H, Fletcher J, Blombery P, Collins R, Wheatley D. Venous thromboembolism prophylaxis guideline implementation is improved by nurse directed feedback and audit. Thromb J. 2011; 9 (1): 7. doi: 10.1186/1477-9560-9-7.

Ho KM, Chavan S, Pilcher D. Omission of early thromboprophylaxis and mortality in critically ill patients: a multicenter registry study. Chest. 2011; 140 (6): 1436-1446. doi: 10.1378/chest.11-1444.

Ho KM, Tan JA. Stratified meta-analysis of intermittent pneumatic compression of the lower limbs to prevent venous thromboembolism in hospitalized patients. Circulation. 2013; 128 (9): 1003-1020.

Institute for Healthcare Improvement (IHI). IHI Improvement Map: Venous Thromboembolus (VTE) Prevention & Treatment. IHI: 2012.  

*Kahn SR, Morrison DR, Cohen JM, Emed J, Tagalakis V, Roussin A, Geerts W. Interventions for implementation of thromboprophylaxis in hospitalized medical and surgical patients at risk for venous thromboembolism. Cochrane Database Syst.Rev. 2013; 7: CD008201.

*Lau BD, Haut ER. Practices to prevent venous thromboembolism: a brief review. BMJ Qual Saf. 2014; 23: 187-195. doi: 10.1136/bmjqs-2012-001782.

Liu DS, Lee MM, Spelman T, MacIsaac C, Cade J, Harley N, Wolff A. Medication chart intervention improves inpatient thromboembolism prophylaxis. Chest. 2012; 141 (3): 632-641. doi: 10.1378/chest.10-3162.

*Maynard G, Morris TA, Jenkins IH, Stone S, Lee J, Renvall M, et al. Optimizing prevention of hospital-acquired venous thromboembolism (VTE): prospective validation of a VTE risk assessment model. J Hosp Med. 2010; 5 (1): 10-18. doi: 10.1002/jhm.562.

Maynard G, Jenkins IH, Merli GJ. Venous thromboembolism prevention guidelines for medical inpatients: mind the (implementation) gap. J Hosp Med. 2013; 8 (10): 582-588. doi: 10.1002/jhm.2071.

Mitchell JD, Collen JF, Petteys S, Holley AB. A simple reminder system improves venous thromboembolism prophylaxis rates and reduces thrombotic events for hospitalized patients. J Thromb Haemost. 2012; 10 (2): 236-243. doi: 10.1111/j.1538-7836.2011.04599.x.

Piazza G, Nguyen TN, Morrison R, Cios D, Hohlfelder B, Fanikos J, et al. Patient education program for venous thromboembolism prevention in hospitalized patients. Am J Med. 2012; 125 (3): 258-264. doi: 10.1016/j.amjmed.2011.09.012.

Pingleton SK, Carlton E, Wilkinson S, Beasley J, King T, Wittkopp C, et al. Reduction of venous thromboembolism (VTE) in hospitalized patients: aligning continuing education with interprofessional team-based quality improvement in an academic medical center. Acad Med. 2013; 88 (10): 1454-1459. doi: 10.1097/ACM.0b013e3182a4aa51.

*Roberts LN, Porter G, Barker RD, Yorke R, Bonner L, Patel RK, Arya R. Comprehensive VTE prevention program incorporating mandatory risk assessment reduces the incidence of hospital-associated thrombosis. Chest. 2013; 144 (4): 1276-1281. doi: 10.1378/chest.13-0267.

Shermock KM, Lau BD, Haut ER, Hobson DB, Ganetsky VS, Kraus PS, et al. Patterns of non-administration of ordered doses of venous thromboembolism prophylaxis: Implications for novel intervention strategies. PLoS One. 2013; 8 (6): e66311. doi:10.1371/journal.pone.0066311.

*Streiff MB, Carolan HT, Hobson DB, et al. Lessons from the Johns Hopkins Multi-Disciplinary Venous Thromboembolism (VTE) Prevention Collaborative. BMJ. 2012; 344: e3935. doi: 10.1136/bmj.e3935.

Thirugnanam S, Pinto R, Cook DJ, Geerts WH, Fowler RA. Economic analyses of venous thromboembolism prevention strategies in hospitalized patients: a systematic review. Crit Care. 2012; 16 (2): R43. doi: 10.1186/cc11241.

Trinh VQ, Karakiewicz PI, Sammon J, Sun M, Sukumar S, Gervais MK, et al. Venous thromboembolism after major cancer surgery: temporal trends and patterns of care. JAMA Surg. 2014; 149 (1): 43-49. doi: 10.1001/jamasurg.2013.3172.

Zeidan AM, Streiff MB, Lau BD, Ahmed SR, Kraus PS, Hobson DB, et al. Impact of a venous thromboembolism prophylaxis "smart order set": Improved compliance, fewer events. Am J Hematol. 2013; 88: 545–549. doi: 10.1002/ajh.23450.